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- SPECIES: Human
- SOURCE SPECIES: Human Cells
- RECOMBINANT PROTEIN SEQUENCE: Lys27-Cys406
- FUSION TAG: C-6 His tag
- APPLICATION NOTE: This recombinant protein can be used for biological assays. For research use only.
- PREDICTED MOLECULAR WEIGHT: 44.6 kD
Properties
- PURITY: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. - PHYSICAL STATE: Liquid
- BUFFER: Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
- STORAGE CONDITIONS: Store at -20°C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: ST6GAL1
- ADDITIONAL NAMES: Beta-Galactoside Alpha-2, 6-Sialyltransferase 1, Alpha 2, 6-ST 1, B-Cell Antigen CD75, CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2, ST6Gal I, ST6GalI, Sialyltransferase 1, ST6GAL1, SIAT1
- Protein Accession Number: P15907
- NCBI GENE ID NUMBER: 6480
Background
- The ST6GAL1 gene encodes beta -Galactosamide alpha-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Gal beta 1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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