SRC Antibody
CATALOG NUMBER: 13-143- Clonality: Polyclonal
- Tested Applications: IP, WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 50 uL
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 410-536 of human SRC (NP_005408.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IP, WB
- APPLICATION NOTE: WB: 1:500 - 1:1000
IP: 1:50 - 1:200 - POSITIVE CONTROL 1: HT-29
- POSITIVE CONTROL 2: DU145
- POSITIVE CONTROL 3: A-549
- POSITIVE CONTROL 4: Mouse brain
- POSITIVE CONTROL 5: Mouse lung
- POSITIVE CONTROL 6: Rat testis
- PREDICTED MOLECULAR WEIGHT: Observed: 60kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: SRC
- ADDITIONAL NAMES: SRC, ASV, Pp60c-src, Tyrosine kinase pp60c-src, Tyrosine-protein kinase SRC-1, v-src, C-SRC, p60-Src, Proto-oncogene c-Src, SRC1
- NCBI GENE ID NUMBER: 6714
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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