SPINT2 Antibody
CATALOG NUMBER: 60-423- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This SPINT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-251 amino acids from the C-terminal region of human SPINT2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 28 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: SPINT2
- ADDITIONAL NAMES: Kunitz-type protease inhibitor 2, Hepatocyte growth factor activator inhibitor type 2, HAI-2, Placental bikunin, SPINT2, HAI2, KOP
- Protein Accession Number: O43291
- NCBI GENE ID NUMBER: 10653
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a transmembrane protein with twoextracellular Kunitz domains that inhibits a variety of serineproteases. The protein inhibits HGF activator which prevents theformation of active hepatocyte growth factor. This gene is aputative tumor suppressor, and mutations in this gene result incongenital sodium diarrhea. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
- 1: Dong, W., et al. Int. J. Cancer 127(7):1526-1534(2010)
- 2: Bergum, C., et al. Prostate 70(13):1422-1428(2010)
- 3: Sivagnanam, M., et al. Clin. Dysmorphol. 19 (1), 48 (2010) :
- 4: Yamauchi, M., et al. Biol. Chem. 383(12):1953-1957(2002)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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