Powered by BiozSpecifications
- SPECIES: Human
- SOURCE SPECIES: HEK293 cells
- RECOMBINANT PROTEIN SEQUENCE: ACPAQCSCSG STVDCHGLAL RSVPRNIPRN TERLDLNGNN ITRITKTDFA GLRHLRVLQL MENKISTIER GAFQDLKELE RLRLNRNHLQ LFPELLFLGT AKLYRLDLSE NQIQAIPRKA FRGAVDIKNL QLDYNQISCI EDGAFRALRD LEVLTLNNNN ITRLSVASFN HMPKLRTFRL HSNNLYCDCH LAWLSDWLRQ RPRVGLYTQC MGPSHLRGHN VAEVQKREFV CSGHQSFMAP SCSVLHCPAA CTCSNNIVDC RGKGLTEIPT NLPETITEIR LEQNTIKVIP PGAFSPYKKL RRIDLSNNQI SELAPDAFQG LRSLNSLVLY GNKITELPKS LFEGLFSLQL LLLNANKINC LRVDAFQDLH NLNLLSLYDN KLQTIAKGTF SPLRAIQTMH LAQNPFICDC HLKWLADYLH TNPIETSGAR CTSPRRLANK RIGQIKSKKF RCSAKEQYFI PGTEDYRSKL SGDCFADLAC PEKCRCEGTT VDCSNQKLNK IPEHIPQYTA ELRLNNNEFT VLEATGIFKK LPQLRKINFS NNKITDIEEG AFEGASGVNE ILLTSNRLEN VQHKMFKGLE SLKTLMLRSN RITCVGNDSF IGLSSVRLLS LYDNQITTVA PGAFDTLHSL STLNLLANPF NCNCYLAWLG EWLRKKRIVT GNPRCQKPYF LKEIPIQDVA IQDFTCDDGN DDNSCSPLSR CPTECTCLDT VVRCSNKGLK VLPKGIPRDV TELYLDGNQF TLVPKELSNY KHLTLIDLSN NRISTLSNQS FSNMTQLLTL ILSYNRLRCI PPRTFDGLKS LRLLSLHGND ISVVPEGAFN DLSALSHLAI GANPLYCDCN MQWLSDWVKS EYKEPGIARC AGPGEMADKL LLTTPSKKFT CQGPVDVNIL AKCNPCLSNP CKNDGTCNSD PVDFYRCTCP YGFKGQDCDV PIHACISNPC KHGGTCHLKE GEEDGFWCIC ADGFEGENCE VNVDDCEDND CENNSTCVDG INNYTCLCPP EYTGELCEEK LDFCAQDLNP CQHDSKCILT PKGFKCDCTP GYVGEHCDID FDDCQDNKCK NGAHCTDAVN GYTCICPEGY SGLFCEFSPP MV
Properties
- PURITY: Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg). - PHYSICAL STATE: Lyophilized
- STORAGE CONDITIONS: The lyophilized Slit2 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Slit2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Slit2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Additional Info
- NCBI OFFICIAL SYMBOL: SLIT2
- ADDITIONAL NAMES: SLIL3, Slit-2, SLIL3, Slit homolog 2 protein
- Protein Accession Number: NP_001276065.1
- PROTEIN GI NUMBER: 574281382
- NCBI GENE ID NUMBER: 9353
Background
- Slit2 is a member of the Slit family that signals through the Roundabout (Robo) receptor as a repellent for axon guidance and neuronal migration, and can also act as a chemoattractant to vascular endothelial cells and a chemotaxis inhibitor for leukocytes. Slit2 is expressed primarily in the fetal lung, kidney, and adult spinal cord, and to a lesser extent in adult adrenal gland, thyroid and trachea. Slit2 is initially synthesized as a 1499 amino acid precursor, which is subsequently cleaved into N-terminal and C-terminal fragments, designated as Slit2-N and Slit2-C respectively. The neurodevelopment related activities, as measured by the ability to repel olfactory bulb axons and to induce branching in dorsal root ganglia axons, are contained only in the N-terminal fragment. Recombinant human Slit2-N is a 1088 amino acid glycoprotein corresponding to the N-terminal portion of the full length Slit2 precursor. Due to glycosylation Slit2-N migrates at an apparent molecular weight of approximately 120.0-140.0 kDa by SDS-PAGE analysis under reducing conditions.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.
New & Featured Products
![HIV-1 p24 Antibody [10A2] (biotin)](https://www.prosci-inc.com/wp-content/uploads/2023/01/HIV-1-p24-Antibody-10A2_WB_PM-7371.gif){kind=small}
HIV-1 p24 Antibody [10A2] (biotin)
CATALOG NUMBER: PM-7371-biotin
![HIV-1 p24 Antibody [9D2F6] (biotin)](https://www.prosci-inc.com/wp-content/uploads/2023/01/HIV-1-p24-Antibody-9D2F6_WB_PM-7369.gif){kind=small}
HIV-1 p24 Antibody [9D2F6] (biotin)
CATALOG NUMBER: PM-7369-biotin
![HIV-1 p24 Antibody [8D7E11] (biotin)](https://www.prosci-inc.com/wp-content/uploads/2023/01/HIV-1-p24-Antibody-8D7E11_WB_PM-7367.gif){kind=small}
HIV-1 p24 Antibody [8D7E11] (biotin)
CATALOG NUMBER: PM-7367-biotin