- Recombinant
Siplizumab (CD2/LFA-2) - Research Grade Biosimilar
CATALOG NUMBER: 10-088- Clonality: Recombinant Monoclonal
- Conjugate: Unconjugated
- Size: 0.1 mg
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- SOURCE SPECIES: CHO cells
- IMMUNOGEN: Humanized / CD2/LFA-2 [Homo sapiens]
- CONJUGATE: Unconjugated
Properties
- PURIFICATION: >95%
- CLONALITY: Recombinant Monoclonal
- ISOTYPE: IgG1-kappa
- BUFFER: PBS buffer pH7.5
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage.
Additional Info
- ADDITIONAL NAMES: MEDI-507, CD2/LFA-2, CD2/LFA-2
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Siplizumab has been shown to cause depletion of T-cells.It is therefore considered to be an immunomodulator in clinical settings where the depletion of T-cells may have clinical benefits,such as certain autoimmune diseases and T-cell cancers.In addition, preclinical studies have also suggested that siplizumab,by binding to the CD2 receptor,may selectively produce cell death and reduce cancerous cells.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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