SGK Antibody
CATALOG NUMBER: XW-7894- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Chicken
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 0.05 mg
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- HOST SPECIES: Chicken
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: 211-431
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Serine/threonine-protein kinase Sgk1 antibody can be used for the detection of Serine/threonine-protein kinase Sgk1 by Western Blot.
- PREDICTED MOLECULAR WEIGHT: 49 kDa (calculated)
Properties
- PURIFICATION: Immunoaffinity Purified
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Phosphate-Buffered Saline. No preservatives added.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: SGK antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: SGK1
- ADDITIONAL NAMES: SGK, SGK, Serine/threonineprotein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1
- Protein Accession Number: NP_005618.2
- PROTEIN GI NUMBER: 25168263
- NCBI GENE ID NUMBER: 6446
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- FUNCTION: Protein kinase that plays an important role in cellular stress response. Activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Mediates cell survival signals, phosphorylates and negatively regulates pro-apoptotic FOXO3A. Phosphorylates NEDD4L, which leads to its inactivation and to the subsequent activation of various channels and transporters such as ENaC, Kv1.3, or EAAT1.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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