SENP5 Antibody
CATALOG NUMBER: 57-708- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Monkey, Mouse
- IMMUNOGEN: This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-747 amino acids from the C-terminal region of human SENP5.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 87 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: SENP5
- ADDITIONAL NAMES: Sentrin-specific protease 5, Sentrin/SUMO-specific protease SENP5, SENP5
- Protein Accession Number: Q96HI0
- PROTEIN GI NUMBER: 296452962
- NCBI GENE ID NUMBER: 205564
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The reversible posttranslational modification of proteinsby the addition of small ubiquitin-like SUMO proteins (see SUMO1;MIM 601912) is required for numerous biologic processes.SUMO-specific proteases, such as SENP5, are responsible for theinitial processing of SUMO precursors to generate a C-terminaldiglycine motif required for the conjugation reaction. They alsohave isopeptidase activity for the removal of SUMO from highmolecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed16738315]).
- 1: Yun, C., et al. J. Cell Biol. 183(4):589-595(2008)
- 2: Ding, X., et al. Oncol. Rep. 20(5):1041-1045(2008)
- 3: Gong, L., et al. J. Biol. Chem. 281(23):15869-15877(2006)
- 4: Di Bacco, A., et al. Mol. Cell. Biol. 26(12):4489-4498(2006)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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