Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 274-400 of human SCN3A (NP_008853.3).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: WB: 1:500 - 1:1000
- POSITIVE CONTROL 1: 293T
- POSITIVE CONTROL 2: HT-1080
- PREDICTED MOLECULAR WEIGHT: Observed: 350kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: SCN3A
- ADDITIONAL NAMES: EIEE62, FFEVF4, NAC3, Nav1.3, sodium channel protein type 3 subunit alpha, brain III voltage-gated sodium channel, sodium channel protein brain III subunit alpha, sodium channel protein type III subunit alpha, sodium channel, voltage gated, type III alpha subunit, sodium channel, voltage-gated, type III, alpha polypeptide, voltage-gated sodium channel subtype III, voltage-gated sodium channel subunit alpha Nav1.3
- NCBI GENE ID NUMBER: 6328
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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