SCD5 Antibody
CATALOG NUMBER: 56-815- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine
- IMMUNOGEN: This SCD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human SCD5.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 38 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: SCD5
- ADDITIONAL NAMES: Stearoyl-CoA desaturase 5, Acyl-CoA-desaturase 4, HSCD5, Stearoyl-CoA 9-desaturase, SCD5, ACOD4, SCD4
- Protein Accession Number: Q86SK9
- PROTEIN GI NUMBER: 162416247
- NCBI GENE ID NUMBER: 79966
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integralmembrane protein of the endoplasmic reticulum that catalyzes theformation of monounsaturated fatty acids from saturated fattyacids. SCD may be a key regulator of energy metabolism with a rolein obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4,have been identified in mouse. In contrast, only 2 SCD isoforms,SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1shares about 85% amino acid identity with all 4 mouse SCD isoforms,as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limitedhomology with the rodent SCDs and appears to be unique to primates(Wang et al., 2005 [PubMed 15907797]).
- 1: Bailey, S.D., et al. Diabetes Care (2010) In press :
- 2: Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- 3: Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- 4: Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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