- Trial Size
SARS-CoV Spike Antibody
CATALOG NUMBER: 3219- Clonality: Polyclonal
- Tested Applications: E
- Host Species: Rabbit
- Species Reactivity: Virus
- Conjugate: Unconjugated
- Size: 0.02 mg | 0.1 mg
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Virus
- HOMOLOGY: Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (14%)
- IMMUNOGEN: Anti-SARS-CoV Spike antibody (3219) was raised against a peptide corresponding to 14 amino acids near the amino of SARS-CoV Spike glycoprotein.
The immunogen is located within the first 50 amino acids of SARS-CoV Spike. - CONJUGATE: Unconjugated
- TESTED APPLICATIONS: E
- APPLICATION NOTE: SARS-CoV Spike antibody can be used for the detection of SARS-CoV Spike protein in ELISA. It will detect 5 ng of free peptide at 1 μg/mL.
Advanced Validation
- ISOFORMS: SARS-CoV Spike has one isoform (1255aa).
Properties
- PURIFICATION: SARS-CoV Spike Antibody is affinity chromatography purified via peptide column.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: SARS-CoV Spike Antibody is supplied in PBS containing 0.02% sodium azide.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: SARS-CoV Spike antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: S
- ADDITIONAL NAMES: SARS-CoV Spike Antibody: E2, Spike glycoprotein, E2, S glycoprotein
- Protein Accession Number: P59594
- PROTEIN GI NUMBER: 30173397
- NCBI GENE ID NUMBER: 1489668
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- SARS-CoV Spike Antibody: A novel coronavirus has been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.
- 1: Marra et al. Science 2003;300:1399-404.
- 2: Rota et al. Science 2003;300:1394-9.
- 3: Navas-Nartin et al. J Neurovirol. 2004;10:75-85.
- 4: Li et al. Nature 2003;426:450-4.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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