Specifications
- SPECIES: SARS-CoV-2 (COVID-19, 2019-nCoV) Spike Protein
- SOURCE SPECIES: E. coli
- RECOMBINANT PROTEIN SEQUENCE: The E.Coli derived recombinant protein contains the Coronavirus 2019 Spike (800-1000 a.a.) immunodominant regions, fused to His tag at C-terminal.
- FUSION TAG: His Tag
Properties
- PURITY: >90% pure as determined SDS-PAGE.
- PHYSICAL STATE: Liquid
- BUFFER: CoV 2019 Spike Protein 1mg/ml solution is supplied in 1x PBS.
- STORAGE CONDITIONS: Store in working aliquots at -20°C. Avoid freeze/thaw cycles.
Background
- A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019. The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2) in humans. While bats are possibly the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
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