SARS-CoV-2 (COVID-19) NSP8 Recombinant Protein
CATALOG NUMBER: 97-097- Tested Applications: WB
- Size: 0.1 mg
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- SPECIES: SARS-CoV-2
- SOURCE SPECIES: E. coli
- RECOMBINANT PROTEIN SEQUENCE: Ala 1 - Gln 198
- FUSION TAG: His Tag at N-terminus
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: This recombinant protein can be used for WB. For research use only.
- PREDICTED MOLECULAR WEIGHT: 22-25 kDa
Properties
- PURITY: >95% as determined by SDS-PAGE.
- PHYSICAL STATE: Liquid
- BUFFER: 20 mM Tris, 250 mM NaCl, pH8.5 with glycerol
- STORAGE CONDITIONS: Working aliquots should be stored at -70°C or lower. Avoid repeated freeze-thaw cycles.
Additional Info
- ADDITIONAL NAMES: NSP8, nsp8, Non-structural protein 8, COVID-19
- Protein Accession Number: YP_009725304.1
Background
- NSP8, forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. By investigating the entire proteome of SARS-CoV-2, six proteins, including the S protein and five non-structural proteins (nsp3, 3CL-pro, and nsp8-10) were predicted to be adhesins, which are crucial to the viral adhering and host invasion. The S, nsp3, and nsp8 proteins were also predicted by Vaxign-ML to induce high protective antigenicity.
- 1: te Velthuis AJ, et al. Nucleic Acids Res. 2012. 40(4):1737-47.
- 2: Edison Ong, et al. doi.org. 2020. 000141.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Shipping Info
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