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SARS-CoV-2 (COVID-19) NSP8 Antibody
CATALOG NUMBER: 9159- Clonality: Polyclonal
- Tested Applications: ELISA, IHC
- Host Species: Rabbit
- Species Reactivity: Virus
- Conjugate: Unconjugated
- Size: 0.02 mg | 0.1 mg
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Virus
- HOMOLOGY: Predicted reactivity based on immunogen sequence: SARS-CoV NSP8 protein: (100%)
- IMMUNOGEN: Anti-SARS-CoV-2 (COVID-19) NSP8 antibody (9159) was raised against a peptide corresponding to 14 amino acids near the center of SARS-CoV-2 (COVID-19) NSP8 protein.
The immunogen is located within 60-110 amino acids of SARS-CoV-2 (COVID-19) NSP8. - CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, IHC
- APPLICATION NOTE: IHC: 0.5 μg/ml.
Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) NSP8 antibody can detect 2 ng of free peptide at 1 μg/mL in ELISA. It can detect SARS-CoV-2 NSP8 recombinant protein by ELISA. All other applications and species not yet tested.
Properties
- PURIFICATION: SARS-CoV-2 (COVID-19) NSP8 Antibody is affinity chromatography purified via peptide column.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: SARS-CoV-2 (COVID-19) NSP8 Antibody is supplied in PBS containing 0.02% sodium azide.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: SARS-CoV-2 (COVID-19) NSP8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: Non-structural protein 8
- ADDITIONAL NAMES: NSP8
- Protein Accession Number: YP_009742615.1
- PROTEIN GI NUMBER: 1826688925
- NCBI GENE ID NUMBER: 43740578
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP8 plays a role in viral RNA synthesis (3,4,5). Forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, it may synthesize substantially longer products than oligonucleotide primers (6).
- 1: Gorbalenya. bioRxiv: 2020.
- 2: Hui et al. Int J Infect Dis. 2020;91:264-266.
- 3: Gao et. al Science 2020;0:0-0
- 4: Yin et. al Science 2020;0:0-0
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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