Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Virus
- HOMOLOGY: Predicted reactivity based on immunogen sequence: SARS-CoV NSP7 protein: (100%)
- IMMUNOGEN: Anti-SARS-CoV-2 (COVID-19) NSP7 antibody (9155) was raised against a peptide corresponding to 12 amino acids near the carboxyl terminus of the SARS-CoV-2 (COVID-19) NSP7 protein.
The immunogen is located within the last 50 amino acids of the SARS-CoV-2 (COVID-19) NSP7 protein. - CONJUGATE: Unconjugated
- TESTED APPLICATIONS: E, IHC
- APPLICATION NOTE: IHC: 0.5 μg/ml.
Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) NSP7 antibody can detect 2 ng of free peptide at 1 μg/mL in ELISA. It can detect SARS-CoV-2 NSP7 recombinant protein by ELISA. All other applications and species not yet tested.
Properties
- PURIFICATION: SARS-CoV-2 (COVID-19) NSP7 Antibody is affinity chromatography purified via peptide column.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: SARS-CoV-2 (COVID-19) NSP7 Antibody is supplied in PBS containing 0.02% sodium azide.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: SARS-CoV-2 (COVID-19) NSP7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: Non-structural protein 7
- ADDITIONAL NAMES: NSP7
- Protein Accession Number: YP_009742614.1
- PROTEIN GI NUMBER: 1826688924
- NCBI GENE ID NUMBER: 43740578
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP7 plays a role in viral RNA synthesis (3,4,5). It forms a hexadecamer with nsp8 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, it may synthesize substantially longer products than oligonucleotide primers.
- 1: Gorbalenya. bioRxiv: 2020.
- 2: Hui et al. Int J Infect Dis. 2020;91:264-266.
- 3: Gao et. al Science 2020;0:0-0
- 4: Yin et. al Science 2020;0:0-0
- 5: Hillen et. al. Nature 2020;0:0-0
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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