Specifications
- SPECIES: SARS-CoV-2 (COVID-19, 2019-nCoV) Nucleocapsid protein
- SOURCE SPECIES: E. coli
- RECOMBINANT PROTEIN SEQUENCE: NA
- FUSION TAG: N-6His tag
- APPLICATION NOTE: This recombinant protein can be used for biological assays. For research use only.
- PREDICTED MOLECULAR WEIGHT: 16.2kDa, 16kDa
Properties
- PURITY: Greater than 95% as determined by reducing SDS-PAGE.
- PHYSICAL STATE: Liquid
- BUFFER: Supplied as a 0.2 uM filtered solution of PBS, 2M Urea, pH 7.4.
- STORAGE CONDITIONS: Reconstituted protein solution should be stored at ≤ -20°C.
Additional Info
- NCBI OFFICIAL SYMBOL: N
- ADDITIONAL NAMES: 2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein
- Protein Accession Number: QHD43423.2
- NCBI GENE ID NUMBER: 43740575
Background
- Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
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