SARS-CoV-2 (COVID-19) Envelope Antibody
CATALOG NUMBER: 20-274- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Sheep
- Species Reactivity: Virus
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Sheep
- SPECIES REACTIVITY: Virus
- IMMUNOGEN: GST-SARS-CoV2 E Protein
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Detection Antibodies: 1 μg/ml Ab, 5% BSA in TBS-T, 4°C overnight
Blocking: 5% milk in TBS-T, 1h room temp
Secondary Antibodies: 1:15,000 donkey anti-sheep, 1:15,000 donkey anti-mouse, in TBS-T, 1h room temp
Wash: TBS-T, 4x 10 min
Properties
- PURIFICATION: Antibodies are affinity purified against the antigen and eluted with low pH.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in PBS.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Aliquot and store at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: E
- ADDITIONAL NAMES: SARS-CoV-2-E Protein, SARS-CoV-2-Envelope Protein
- NCBI GENE ID NUMBER: 43740570
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Coronavirus envelope (E) proteins are short (1 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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