S100A14 Recombinant Protein
CATALOG NUMBER: 96-667- Tested Applications: WB
- Size: 0.1 mg
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- SPECIES: Human
- SOURCE SPECIES: E. coli
- RECOMBINANT PROTEIN SEQUENCE: Met 1 - His 104
- FUSION TAG: His Tag
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: This recombinant protein can be used for WB. For research use only.
- PREDICTED MOLECULAR WEIGHT: 12.5 kDa
Properties
- PURITY: >92% as determined by SDS-PAGE.
- PHYSICAL STATE: Lyophilized
- BUFFER: 50 mM Tris,150 mM NaCl,pH8.0
- STORAGE CONDITIONS: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: S100A14
- ADDITIONAL NAMES: S100A14, S114, S100A15
- Protein Accession Number: AAH05019
- NCBI GENE ID NUMBER: 57402
Background
- Protein S100-A14 (S100A14) is also known as S100 calcium-binding protein A14 (S114),which belongs to the S-100 family, containing one EF-hand domain.S100A14 is a homodimer can interact with AGER. S100A14 can modulate P53/TP53 protein levels, and play a role in the regulation of cell survival and apoptosis at different concentrations via receptor for advanced glycation end products (RAGE).S100A14 also plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53.
- 1: Jin Q., et al., 2011, PLoS ONE 6:E19375-E19375.
- 2: Chen H., et al., 2012, J. Biol. Chem. 287:17109-17119.
- 3: Sapkota D., et al., 2012, Oral Oncol. 48:219-225.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Shipping Info
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