Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Dog, Human, Mouse, Rat, Zebrafish
- IMMUNOGEN: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNF2.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: ELISA, IHC, WB
- APPLICATION NOTE: RNF2 antibody can be used for detection of RNF2 by ELISA at 1:312500. RNF2 antibody can be used for detection of RNF2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- POSITIVE CONTROL 1: Cat. No. 1211 - HepG2 Cell Lysate
- PREDICTED MOLECULAR WEIGHT: 29 kDa
Properties
- PURIFICATION: Antibody is purified by protein A chromatography method.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: For short periods of storage (days) store at 4°C. For longer periods of storage, store RNF2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: RNF2
- ADDITIONAL NAMES: RNF2, BAP1, DING, BAP-1, HIPI3, RING2, RING1B
- Protein Accession Number: NP_009143
- PROTEIN GI NUMBER: 6005747
- NCBI GENE ID NUMBER: 6045
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by RNF2 is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
- 1: Voncken, J.W., et al., (2003) Proc Natl Acad Sci U.S.A. 4 100(5), 2468-73.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: This product is for research use only.
Shipping Info
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