Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This RNASEH2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-157 amino acids from the Central region of human RNASEH2B.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100 - PREDICTED MOLECULAR WEIGHT: 35 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: RNASEH2B
- ADDITIONAL NAMES: Ribonuclease H2 subunit B, RNase H2 subunit B, Aicardi-Goutieres syndrome 2 protein, AGS2, Deleted in lymphocytic leukemia 8, Ribonuclease HI subunit B, RNASEH2B, DLEU8
- Protein Accession Number: Q5TBB1
- PROTEIN GI NUMBER: 74745929
- NCBI GENE ID NUMBER: 79621
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- RNASEH2B is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. RNASEH2B is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication.
- 1: Crozat, K., et al. Immunol. Rev. 227(1):129-149(2009)
- 2: Chon, H., et al. Nucleic Acids Res. 37(1):96-110(2009)
- 3: Crow, Y.J., et al. Dev Med Child Neurol 50(6):410-416(2008)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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