Specifications
- HOST SPECIES: Chicken
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: 111-246
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: RGS11 (M-136) antibody can be used for the detection of RGS11 (M-136) by Western blot, may also work for IHC and ICC.
- PREDICTED MOLECULAR WEIGHT: 52.9 kDa (calculated)
Properties
- PURIFICATION: Antigen affinity-purified
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Phosphate-Buffered Saline. No preservatives added.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: RGS11 (M-136) antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: RGS11
- ADDITIONAL NAMES: Regulator of G-protein signaling 11RGS11, RS11,
- Protein Accession Number: NP_899180.1
- PROTEIN GI NUMBER: 34452688
- NCBI GENE ID NUMBER: 8786
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Regulator of G-protein signalling 11. This protein belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the α subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein α subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
- 1: Snow,B. E., Krumins,A. M., Brothers,G. M., Lee,S. F., Wall,M. A., Chung,S., Mangion,J., Arya,S., Gilman,A. G. and Siderovski,D. P. A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits. Proc. Natl. Acad. Sci. U. S. A. 95 (22), 13307-13312 (1998).
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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