- Recombinant
Reslizumab (IL5) - Research Grade Biosimilar
CATALOG NUMBER: 10-291- Clonality: Recombinant Monoclonal
- Conjugate: Unconjugated
- Size: 0.1 mg
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- SOURCE SPECIES: CHO cells
- IMMUNOGEN: Humanized / IL5 [Homo sapiens]
- CONJUGATE: Unconjugated
Properties
- PURIFICATION: >95%
- CLONALITY: Recombinant Monoclonal
- ISOTYPE: IgG4-nd
- BUFFER: PBS buffer pH7.5
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage.
Additional Info
- ADDITIONAL NAMES: CDP-835,JES1-39D10,SCH55700
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of IL-5. Reslizumab inhibits IL-5-dependent cell proliferation, with an IC50 value of approximately 91.1pM. Reslizumab has high binding affinity for human IL-5, with KD values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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