Specifications
- HOST SPECIES: Goat
- SPECIES REACTIVITY: Human, Mouse, Rat
- HOMOLOGY: Expected Species Reactivity based on sequence homology: Dog, Cow
- IMMUNOGEN: The immunogen for this antibody is: C-VSIDNKKRNI
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: E, WB
- APPLICATION NOTE: Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 38+35kDa bands observed in Human Heart lysates, 37kDa band observed in Mouse Heart lysates and approx 35kDa in Rat Heart lysates (calculated MW of 37.8 and 34.9 according to Human NP_001026879.2 and NP_060833.1 resp, of 33.3kDa according to Mouse NP_001161290.1 and of 35.0kDa according to Rat NP_001014189.1). Recommended concentration: 1-3ug/ml. Primary incubation was 1 hour.
- SPECIFICITY: This antibody is expected to recognise both reported isoforms (NP_001026879.2 and NP_060833.1).
- POSITIVE CONTROL 1: Cat. No. 1305 - Human Kidney Tissue Lysate
Properties
- PURIFICATION: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing.
- CONCENTRATION: 500 ug/mL
- STORAGE CONDITIONS: Aliquot and store at -20°C. Minimize freezing and thawing.
Additional Info
- NCBI OFFICIAL SYMBOL: RNLS
- ADDITIONAL NAMES: RNLS, renalase, C10orf59, chromosome 10 open reading frame 59 , HGNC:25641, FLJ11218 , hypothetical protein LOC55328, renalase, FAD-dependent amine oxidase, RENALASE
- Protein Accession Number: NP_001026879.2,NP_060833.1
- PROTEIN GI NUMBER: 72534708
- NCBI GENE ID NUMBER: 55328
Background
- 1: Xu J, Li G, Wang P, Velazquez H, Yao X, Li Y, Wu Y, Peixoto A, Crowley S, Desir GV. Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure. J Clin Invest. 2005 May 2;115(5):1275-1280. Epub 2005 Apr 7.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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