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Home / Bovine / Recombinant CD79a Antibody [IGA/1790R]
Recombinant CD79a Antibody [IGA/1790R]Recombinant CD79a Antibody [IGA/1790R]Recombinant CD79a Antibody [IGA/1790R]Recombinant CD79a Antibody [IGA/1790R]
Recombinant CD79a Antibody [IGA/1790R]
Recombinant CD79a Antibody [IGA/1790R]
Recombinant CD79a Antibody [IGA/1790R]
Recombinant CD79a Antibody [IGA/1790R]
  • Recombinant

Recombinant CD79a Antibody [IGA/1790R]

CATALOG NUMBER: 33-837
  • Clonality: Recombinant Monoclonal
  • Tested Applications: IHC-P, WB
  • Host Species: Rabbit
  • Species Reactivity: Bovine, Human, Monkey, Mouse, Pig, Rat
  • Conjugate: Unconjugated
  • Size: 100 ug

Specifications

  • HOST SPECIES: Rabbit
  • SPECIES REACTIVITY: Bovine, Human, Monkey, Mouse, Pig, Rat
  • IMMUNOGEN: Amino acids 202-216 (GTYQDVGSLNIADVQ) were used as the immunogen for the recombinant CD79a antibody.
  • CONJUGATE: Unconjugated
  • TESTED APPLICATIONS: IHC-P, WB
  • APPLICATION NOTE: Western blot: 0.5-1 ug/ml
    Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
    Prediluted IHC only format: incubate for 30 min at RT

Properties

  • PURIFICATION: Protein A affinity chromatography
  • CLONALITY: Recombinant Monoclonal
  • ISOTYPE: IgG, k
  • PHYSICAL STATE: Liquid
  • BUFFER: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
  • CONCENTRATION: 0.2 mg/mL
  • STORAGE CONDITIONS: Aliquot and Store at 2-8°C. Avoid freez-thaw cycles.

Additional Info

  • NCBI OFFICIAL SYMBOL: CD79A
  • ADDITIONAL NAMES: B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, CD79A, IGA, MB1
  • NCBI GENE ID NUMBER: 973
  • USER NOTE: Optimal dilutions for each application to be determined by the researcher

Background

  • A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.

Disclaimer

  • FOR RESEARCH USE ONLY
    For additional information, visit ProSci's Terms & Conditions Page.
  • Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER: 33-837

  • Size: 100 ug
  • List Price: $555.00
Datasheet
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