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![Recombinant Cadherin 16 Antibody [CDH16/1532R]](https://www.prosci-inc.com/wp-content/uploads/2021/11/Recombinant-Cadherin-16-Antibody-CDH161532R_IHC_34-077_2.jpg){kind=small}
![Recombinant Cadherin 16 Antibody [CDH16/1532R]](https://www.prosci-inc.com/wp-content/uploads/2021/11/Recombinant-Cadherin-16-Antibody-CDH161532R_IHC_34-077_3.jpg){kind=small}
Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Human protein was used as the immunogen for the recombinant Cadherin 16 antibody.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, IF, IHC-P
- APPLICATION NOTE: Flow Cytometry: 0.5-1ug/10e6 cells
Immunofluorescence: 1-2 ug/ml
Immunohistochemistry (FFPE): 0.5-1 ug/ml for 30 min at RT
Prediluted IHC only format: incubate for 30 min at RT (1)
Optimal dilution of the recombinant Cadherin 16 antibody to be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Properties
- PURIFICATION: Protein A affinity chromatography
- CLONALITY: Recombinant Monoclonal
- ISOTYPE: IgG, kappa
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
- CONCENTRATION: 0.2 mg/mL
- STORAGE CONDITIONS: Aliquot and Store at 2-8°C. Avoid freez-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: CDH16
- ADDITIONAL NAMES: Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
- NCBI GENE ID NUMBER: 1014
- USER NOTE: Optimal dilutions for each application to be determined by the researcher
Background
- Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.
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