RCBTB1 Antibody
CATALOG NUMBER: 58-739- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This RCBTB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-377 amino acids from the Central region of human RCBTB1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 58 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: RCBTB1
- ADDITIONAL NAMES: RCC1 and BTB domain-containing protein 1, Chronic lymphocytic leukemia deletion region gene 7 protein, CLL deletion region gene 7 protein, Regulator of chromosome condensation and BTB domain-containing protein 1, RCBTB1, CLLD7, E45
- Protein Accession Number: Q8NDN9
- PROTEIN GI NUMBER: 74751227
- NCBI GENE ID NUMBER: 55213
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a protein with an N-terminal RCC1 domainand a C-terminal BTB (broad complex, tramtrack and bric-a-brac)domain. In rat, over-expression of this gene in vascular smoothmuscle cells induced cellular hypertrophy. In rat, the C-terminusof RCBTB1 interacts with the angiotensin II receptor-1A. In humans,this gene maps to a region of chromosome 13q that is frequentlydeleted in B-cell chronic lymphocytic leukemia and other lymphoidmalignancies.
- 1: Genuneit, J., et al. Clin. Exp. Allergy 39(12):1875-1888(2009)
- 2: Guo, D.F., et al. J. Biol. Chem. 279(20):21109-21120(2004)
- 3: Dunham, A., et al. Nature 428(6982):522-528(2004)
- 4: Solomou, E.E., et al. Leuk. Lymphoma 44(9):1579-1585(2003)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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