Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: A recombinant protein fragment from the C-terminus of human RAX was used as the immunogen for this antibody.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Western blot: 1-3 ug/ml
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Properties
- PURIFICATION: Protein A affinity chromatography
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
- CONCENTRATION: 0.5 mg/mL
- STORAGE CONDITIONS: Aliquot and Store at -20°C. Avoid freez-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: RAX
- ADDITIONAL NAMES: Retinal homeobox protein Rx, Retina and anterior neural fold homeobox protein, RAX, RX
- NCBI GENE ID NUMBER: 30062
- USER NOTE: Optimal dilutions for each application to be determined by the researcher
Background
- Rax (Retinal and anterior neural fold homeobox), a paired-type homeobox protein, is a human homolog of Drosophila Rx protein. It is a marker of developing eye and forebrain in vertebrates, initially expressed in the region of the forebrain where optic vesicles are formed, and is involved in promoting the division of retinal progenitor cells early in development. As development progresses, expression is seen in the retina and hypothalamus. RAX is essential for eye development. Knockout of RAX in mice eliminated eye development, and RAX mutation in humans result in Anophthalmia, where one or both eyes fail to develop.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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