Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This PYHIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human PYHIN1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 55 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: PYHIN1
- ADDITIONAL NAMES: Pyrin and HIN domain-containing protein 1, Interferon-inducible protein X, PYHIN1, IFIX
- Protein Accession Number: Q6K0P9
- PROTEIN GI NUMBER: 74748871
- NCBI GENE ID NUMBER: 149628
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- PYHIN1 belongs to the HIN200 family ofinterferon-inducible proteins that share a 200-amino acid signaturemotif at their C-terminal ends. HIN200 proteins are primarilynuclear and are involved in transcriptional regulation of genesimportant for cell cycle control, differentiation, and apoptosis(Ding et al., 2006 [PubMed 16479015]).
- 1: Yamaguchi, H., et al. Mol. Carcinog. 47(10):739-743(2008)
- 2: Ding, Y., et al. Mol. Cell. Biol. 26(5):1979-1996(2006)
- 3: Ding, Y., et al. Oncogene 23(26):4556-4566(2004)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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