PTPRG Antibody
CATALOG NUMBER: 58-007- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Mouse
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Mouse
- IMMUNOGEN: This PTPRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-700 amino acids from the Central region of human PTPRG.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 162 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: PTPRG
- ADDITIONAL NAMES: Receptor-type tyrosine-protein phosphatase gamma, Protein-tyrosine phosphatase gamma, R-PTP-gamma, PTPRG, PTPG
- Protein Accession Number: P23470
- PROTEIN GI NUMBER: 229463033
- NCBI GENE ID NUMBER: 5793
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The protein encoded by this gene is a member of theprotein tyrosine phosphatase (PTP) family. PTPs are known to besignaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, mitotic cycle, andoncogenic transformation. This PTP possesses an extracellularregion, a single transmembrane region, and two tandemintracytoplasmic catalytic domains, and thus represents areceptor-type PTP. The extracellular region of this PTP contains acarbonic anhydrase-like (CAH) domain, which is also found in theextracellular region of PTPRBETA/ZETA. This gene is located in achromosomal region that is frequently deleted in renal cellcarcinoma and lung carcinoma, thus is thought to be a candidatetumor suppressor gene.
- 1: Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- 2: Shu, S.T., et al. Anticancer Res. 30(6):1937-1946(2010)
- 3: Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
- 4: Bouyain, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(6):2443-2448(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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