PTPN1 Antibody
CATALOG NUMBER: XW-7826- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Chicken
- Species Reactivity: Human, Rat
- Conjugate: Unconjugated
- Size: 0.05 mg
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- HOST SPECIES: Chicken
- SPECIES REACTIVITY: Human, Rat
- IMMUNOGEN: 288-364
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Tyrosine-protein phosphatase non-receptor type 1 antibody can be used for the detection of Tyrosine-protein phosphatase non-receptor type 1 by Western Blot.
- PREDICTED MOLECULAR WEIGHT: 50 kDa (calculated)
Properties
- PURIFICATION: Immunoaffinity Purified
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Phosphate-Buffered Saline. No preservatives added.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: PTPN1 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: PTPN1
- ADDITIONAL NAMES: PTP1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, PTP1B, Tyrosineprotein phosphatase nonreceptor type 1
- Protein Accession Number: NP_002818.1
- PROTEIN GI NUMBER: 4506289
- NCBI GENE ID NUMBER: 5770
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- FUNCTION: May play an important role in CKII- and p60c-src-induced signal transduction cascades (By similarity).
CATALYTIC ACTIVITY: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
PTM: Oxidized on Cys-215; the Cys-SOH formed in response to redox signaling reacts with the α-amido of the following residue to form a 4-amino-3-isothiazolidinone serine cross-link, triggering a conformational change that inhibits substrate binding and activity. The active site can be restored by reduction.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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