![Progesterone Receptor Antibody [SPM566]](https://www.prosci-inc.com/wp-content/uploads/2021/11/Progesterone-Receptor-Antibody-SPM566_IHC_34-152_1.jpg){kind=small}
Progesterone Receptor Antibody [SPM566]
CATALOG NUMBER: 34-152- Clonality: Monoclonal
- Tested Applications: IHC
- Host Species: Mouse
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 100 ug
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- HOST SPECIES: Mouse
- SPECIES REACTIVITY: Human
- IMMUNOGEN: Recombinant human protein was used as the immunogen for this anti-Progesterone Receptor antibody.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC
- APPLICATION NOTE: Immunohistochemistry (FFPE): 0.5-1 ug/ml for 30 min at RT
Prediluted format: incubate for 30 min at RT (2)
The optimal dilution of the anti-Progesterone Receptor antibody for each application should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Properties
- PURIFICATION: Protein G affinity chromatography
- CLONALITY: Monoclonal
- ISOTYPE: IgG1, kappa
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
- CONCENTRATION: 0.2 mg/mL
- STORAGE CONDITIONS: Aliquot and Store at 2-8°C. Avoid freez-thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: PGR
- ADDITIONAL NAMES: Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3
- NCBI GENE ID NUMBER: 5241
- USER NOTE: Optimal dilutions for each application to be determined by the researcher
Background
- This mAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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