Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: PRL-3 antibody was raised against a peptide sequence around aa. 161-166 (K-D-P-H-T) derived from Human PTP4A3.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Western Blot: 1:500~1:1000
- SPECIFICITY: This antibody detects transfected PRL-3 protein.
- PREDICTED MOLECULAR WEIGHT: 22 kDa
Properties
- PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: Store antibody at -20°C for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: PTP4A3
- ADDITIONAL NAMES: PRL3, PRL-3, PRL-R, HDACL1, CDA07, protein tyrosine phosphatase type IVA, PRL3, PTP4A3
- Protein Accession Number: NP_116000
- PROTEIN GI NUMBER: 14589856
- NCBI GENE ID NUMBER: 11156
Background
- Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
- 1: Matter W. F. et. al. Biochem. Biophys. Res. Commun. 283:1061-1068 (2001) Wang J. et. al. J. Biol. Chem. 277:46659-46668 (2002)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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