PRKAR1B Antibody
CATALOG NUMBER: 59-017- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This PRKAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the N-terminal region of human PRKAR1B.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 43 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: PRKAR1B
- ADDITIONAL NAMES: cAMP-dependent protein kinase type I-beta regulatory subunit, PRKAR1B
- Protein Accession Number: P31321
- PROTEIN GI NUMBER: 229463042
- NCBI GENE ID NUMBER: 5575
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Cyclic AMP-dependent protein kinase A (PKA) is anessential enzyme in the signaling pathway of the second messengercAMP. Through phosphorylation of target proteins, PKA controls manybiochemical events in the cell including regulation of metabolism,ion transport, and gene transcription. The PKA holoenzyme iscomposed of 2 regulatory and 2 catalytic subunits and dissociatesfrom the regulatory subunits upon binding of cAMP.[supplied byOMIM].
- 1: Silva, L.K., et al. Eur. J. Hum. Genet. (2010) In press :
- 2: Liu, Y.J., et al. Obesity (Silver Spring) (2010) In press :
- 3: Zhan, X., et al. Anal. Biochem. 354(2):279-289(2006)
- 4: Gullingsrud, J., et al. Structure 14(1):141-149(2006)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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