PPP1R16B Antibody
CATALOG NUMBER: 59-308- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse
- IMMUNOGEN: This PPP1R16B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-399 amino acids from the Central region of human PPP1R16B.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 64 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: PPP1R16B
- ADDITIONAL NAMES: Protein phosphatase 1 regulatory inhibitor subunit 16B, Ankyrin repeat domain-containing protein 4, CAAX box protein TIMAP, TGF-beta-inhibited membrane-associated protein, hTIMAP, PPP1R16B, ANKRD4, KIAA0823
- Protein Accession Number: Q96T49
- PROTEIN GI NUMBER: 22256977
- NCBI GENE ID NUMBER: 26051
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The protein encoded by this gene is membrane-associatedand contains five ankyrin repeats, a proteinphosphatase-1-interacting domain, and a carboxy-terminal CAAX boxdomain. Synthesis of the encoded protein is inhibited bytransforming growth factor beta-1. The protein may bind to themembrane through its CAAX box domain and may act as a signalingmolecule through interaction with protein phosphatase-1.Alternatively spliced transcript variants encoding differentisoforms have been identified in this gene.
- 1: Csortos, C., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 295 (3), L440-L450 (2008) :
- 2: Kim, K., et al. Biochem. Biophys. Res. Commun. 338(3):1327-1334(2005)
- 3: Homma, K., et al. J. Mol. Biol. 343(5):1207-1220(2004)
- 4: Cao, W., et al. Am. J. Physiol., Cell Physiol. 283 (1), C327-C337 (2002) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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