Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 287-526 of human PODXL (NP_005388.2).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IF, WB
- APPLICATION NOTE: WB: 1:1000 - 1:2000
IF: 1:100 - 1:200 - POSITIVE CONTROL 1: HeLa
- POSITIVE CONTROL 2: HepG2
- POSITIVE CONTROL 3: SW480
- POSITIVE CONTROL 4: HT-1080
- POSITIVE CONTROL 5: 293T
- POSITIVE CONTROL 6: Mouse heart
- PREDICTED MOLECULAR WEIGHT: Observed: 95kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: PODXL
- ADDITIONAL NAMES: PODXL, Gp200, MGC138240, PCLP, PC, PCLP-1
- NCBI GENE ID NUMBER: 5420
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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