Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This PNPLA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the N-terminal region of human PNPLA8.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 88 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: PNPLA8
- ADDITIONAL NAMES: Calcium-independent phospholipase A2-gamma, Intracellular membrane-associated calcium-independent phospholipase A2 gamma, iPLA2-gamma, PNPLA-gamma, Patatin-like phospholipase domain-containing protein 8, iPLA2-2, PNPLA8, IPLA22, IPLA2G
- Protein Accession Number: Q9NP80
- PROTEIN GI NUMBER: 74734299
- NCBI GENE ID NUMBER: 50640
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- PNPLA8 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function.
- 1: Harper, M.T., et al. J. Thromb. Haemost. 6(10):1819-1821(2008)
- 2: Wilson, P.A., et al. J. Lipid Res. 47(9):1940-1949(2006)
- 3: Murakami, M., et al. J. Biol. Chem. 280(14):14028-14041(2005)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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