PMS1 Antibody
CATALOG NUMBER: 58-143- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This PMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 694-722 amino acids from the C-terminal region of human PMS1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 106 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: PMS1
- ADDITIONAL NAMES: PMS1 protein homolog 1, DNA mismatch repair protein PMS1, PMS1, PMSL1
- Protein Accession Number: P54277
- PROTEIN GI NUMBER: 1709683
- NCBI GENE ID NUMBER: 5378
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a protein belonging to the DNA mismatchrepair mutL/hexB family. This protein is thought to be involved inthe repair of DNA mismatches, and it can form heterodimers withMLH1, a known DNA mismatch repair protein. Mutations in this genecause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3)either alone or in combination with mutations in other genesinvolved in the HNPCC phenotype, which is also known as Lynchsyndrome.
- 1: Hong, K.W., et al. J. Hum. Genet. 55(6):336-341(2010)
- 2: Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
- 3: Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
- 4: Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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