PLCD3 Antibody
CATALOG NUMBER: 57-887- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Mouse
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Mouse
- IMMUNOGEN: This PLCD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human PLCD3.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 89 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: PLCD3
- ADDITIONAL NAMES: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3, Phosphoinositide phospholipase C-delta-3, Phospholipase C-delta-3, PLC-delta-3, PLCD3, KIAA1964
- Protein Accession Number: Q8N3E9
- PROTEIN GI NUMBER: 158706388
- NCBI GENE ID NUMBER: 113026
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a member of the phospholipase C family,which catalyze the hydrolysis of phosphatidylinositol4,5-bisphosphate to generate the second messengers diacylglyceroland inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3mediate a variety of cellular responses to extracellular stimuli byinducing protein kinase C and increasing cytosolic Ca(2+)concentrations. This enzyme localizes to the plasma membrane andrequires calcium for activation. Its activity is inhibited byspermine, sphingosine, and several phospholipids. [provided byRefSeq].
- 1: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 2: Segat, L., et al. Vaccine 28(10):2201-2206(2010)
- 3: Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- 4: Newton-Cheh, C., et al. Nat. Genet. 41(6):666-676(2009)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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