PKCD (phospho Tyr64) Antibody
CATALOG NUMBER: 79-973- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: PKCD (phospho Tyr64) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 64 (H-I-Y (p)-E-G) derived from Human PKCD.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Western Blot: 1:500~1:1000
- SPECIFICITY: The antibody detects endogenous level of PKCD only when phosphorylated at tyrosine 64.
- PREDICTED MOLECULAR WEIGHT: 78 kDa
Properties
- PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: Store antibody at -20°C for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: PRKCD
- ADDITIONAL NAMES: KPCD, PKC-delta, PRKCD, kinase PKC-delta, nPKC-delta
- Protein Accession Number: NP_006245.2
- PROTEIN GI NUMBER: 31377782
- NCBI GENE ID NUMBER: 5580
Background
- Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses.
- 1: Wie SM, et al. (2014)J Biol Chem. Adwan TS, et al. (2011)J Biol Chem 286, 35716-24. Lomonaco SL, et al. (2008) J Biol Chem 283, 17731-9.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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