PGR Antibody
CATALOG NUMBER: 60-739- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat
- IMMUNOGEN: This PGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 833-861 amino acids from the C-terminal region of human PGR.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 99 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: PGR
- ADDITIONAL NAMES: Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3
- Protein Accession Number: P06401
- PROTEIN GI NUMBER: 90110048
- NCBI GENE ID NUMBER: 5241
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a member of the steroid receptorsuperfamily. The encoded protein mediates the physiological effectsof progesterone, which plays a central role in reproductive eventsassociated with the establishment and maintenance of pregnancy.This gene uses two distinct promotors and translation start sitesin the first exon to produce two isoforms, A and B. The twoisoforms are identical except for the additional 165 amino acidsfound in the N-terminus of isoform B and mediate their own responsegenes and physiologic effects with little overlap. The location oftranscription initiation for isoform A has not been clearlydetermined.
- 1: Geradts, J., et al. Cancer Invest. 28(9):969-977(2010)
- 2: Tang, P., et al. Cancer Invest. 28(9):978-982(2010)
- 3: Van Belle, V., et al. J. Clin. Oncol. 28(27):4129-4134(2010)
- 4: Taylor, K.C., et al. Horm Res Paediatr (2010) In press :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.
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