- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 63-180 of human PGA5 (NP_055039.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: WB: 1:500 - 1:2000
- POSITIVE CONTROL 1: U-87MG
- POSITIVE CONTROL 2: HT-29
- POSITIVE CONTROL 3: 293T
- POSITIVE CONTROL 4: Mouse brain
- POSITIVE CONTROL 5: Mouse stomach
- POSITIVE CONTROL 6: Rat brain
- PREDICTED MOLECULAR WEIGHT: Observed: 42kDa
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
- NCBI OFFICIAL SYMBOL: PGA5
- ADDITIONAL NAMES: Pepsin A-5, Pepsinogen-5, PGA5
- NCBI GENE ID NUMBER: 5222
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
- This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.
- FOR RESEARCH USE ONLY
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- Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
CATALOG NUMBER: 14-720
- Size: 50 uL
- List Price: $285.00
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