Close Hamburger Menu Close Hamburger Menu
Home / Detection Sets / PDL1 ELISA Matched Antibody Pair (Risk Free)
PDL1 ELISA Matched Antibody Pair (Risk Free)PDL1 Antibody [1D7]PDL1 Antibody [1D7]PDL1 Antibody [1D7]PDL1 Antibody [1D7]PDL1 Antibody [1D7]PDL1 Antibody [1D7]PDL1 Antibody [1D7]PDL1 Antibody [1D7]PDL1 Antibody [8E12] (biotin)
PDL1 ELISA Matched Antibody Pair (Risk Free)
PDL1 Antibody [1D7]
PDL1 Antibody [1D7]
PDL1 Antibody [1D7]
PDL1 Antibody [1D7]
PDL1 Antibody [1D7]
PDL1 Antibody [1D7]
PDL1 Antibody [1D7]
PDL1 Antibody [1D7]
PDL1 Antibody [8E12] (biotin)

PDL1 ELISA Matched Antibody Pair (Risk Free)

CATALOG NUMBER: RFP-0307
  • Clonality: Monoclonal
  • Tested Applications: ELISA
  • Host Species: Mouse
  • Species Reactivity: Human
  • Size: 1 Set

Specifications

  • HOST SPECIES: Mouse
  • SPECIES REACTIVITY: Human
  • IMMUNOGEN: PD-L1 antibodies were raised against the extracellular domain of human PD-L1.
  • TESTED APPLICATIONS: ELISA
  • SET CONTENTS: Capture: PD-L1 Antibody [1D7], Cat. No. RF16038 (100 μg)

    Detection: PD-L1 Antibody [8E12] (biotin), Cat. No. RF16032-biotin (100 μg)

Properties

  • PURIFICATION: Antibodies are supplied as protein A purified IgG1.
  • CLONALITY: Monoclonal
  • ISOTYPE: IgG1
  • PHYSICAL STATE: Liquid
  • BUFFER: PBS containing 0.02% sodium azide.
  • CONCENTRATION: Antibody 1 mg/mL
  • STORAGE CONDITIONS: Antibodies can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

  • USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background

  • Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications
  • 1: Holling TM, Schooten E, and van Den Elsing PJ. Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. Hum. Immunol. 2004; 65:282-90.
  • 2: Ishida Y, Agata Y, Shibahara K, et al. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J. 1992; 11:3887-95.
  • 3: LaGier J and Pober JS. Immune accessory functions of human endothelial cells are modulated by overexpression of B7-H1 (PDL1). Hum. Immunol. 2006; 67:568-78.
  • 4: Aydin AM, Woldu SL, Hutchinson RC, et al. Spotlight on atezolizumab and its potential in the treatment of advanced urothelial bladder cancer.Onco. Targets Ther. 2017;10:1487-502.

Set Contents

Disclaimer

  • FOR RESEARCH USE ONLY
    For additional information, visit ProSci's Terms & Conditions Page.
  • Disclaimer: This product is for research use only.

CATALOG NUMBER: RFP-0307

  • Size: 1 Set
  • List Price: $535.00
Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services 

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products
HIV-1 p24 Antibody [10A2] (biotin)
HIV-1 p24 Antibody [10A2] (biotin)

CATALOG NUMBER: PM-7371-biotin

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [8D7E11] (biotin)
HIV-1 p24 Antibody [8D7E11] (biotin)

CATALOG NUMBER: PM-7367-biotin