PDE4A Antibody
CATALOG NUMBER: 59-005- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse
- IMMUNOGEN: This PDE4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human PDE4A.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 98 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: PDE4A
- ADDITIONAL NAMES: cAMP-specific 3',5'-cyclic phosphodiesterase 4A, DPDE2, PDE46, PDE4A, DPDE2
- Protein Accession Number: P27815
- PROTEIN GI NUMBER: 116242706
- NCBI GENE ID NUMBER: 5141
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- Cyclic nucleotides are important second messengers thatregulate and mediate a number of cellular responses toextracellular signals, such as hormones, light, andneurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs)regulate the cellular concentrations of cyclic nucleotides andthereby play a role in signal transduction. PDE4A is a class IVcAMP-specific PDE (summary by Milatovich et al., 1994 [PubMed8009369]).
- 1: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 2: Selige, J., et al. J. Cell. Physiol. 223(2):317-326(2010)
- 3: Bjorgo, E., et al. Mol. Cell. Biol. 30(7):1660-1672(2010)
- 4: Singh, D., et al. Respir. Res. 11, 26 (2010) :
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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