- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Paxillin (Phospho-Tyr118) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 118 (H-V-Y (p) -S-F) derived from Human Paxillin.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC, WB
- APPLICATION NOTE: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
- SPECIFICITY: This antibody detects endogenous level of Paxillin only when phosphorylated at tyrosine 118.
- PREDICTED MOLECULAR WEIGHT: 68 kDa
- PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: Store antibody at -20°C for up to one year.
- NCBI OFFICIAL SYMBOL: PXN
- ADDITIONAL NAMES: IKBA, MAD3, NFKBI, PAXI, PXN
- Protein Accession Number: NP_001074324.1
- PROTEIN GI NUMBER: 170932514
- NCBI GENE ID NUMBER: 5829
- Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
- 1: Tao WA, et al. (2005) Nat Methods. 2 (8): 591-598. Zhang Y, et al. (2005) Mol Cell Proteomics. 4 (9): 1240-1250. Sanders MA, et al. (2005) J Biol Chem. 280 (25): 23516-23522. Rush J, et al. (2004) Nat Biotechnol. 23 (1): 94-101.
- FOR RESEARCH USE ONLY
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- Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
CATALOG NUMBER: 79-144
- Size: 0.1 mg
- List Price: $325.00
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