p70 S6 Kinase (Ab 421) Antibody
CATALOG NUMBER: 79-382- Clonality: Polyclonal
- Tested Applications: IHC, WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: p70 S6 Kinase (Ab-421) antibody was raised against a peptide sequence around aa.419~423 (P-R-T-P-V) derived from Human p70 S6 Kinase.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC, WB
- APPLICATION NOTE: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
- SPECIFICITY: This antibody detects endogenous level of total p70 S6 Kinase protein.
- PREDICTED MOLECULAR WEIGHT: 70 85 kDa
Properties
- PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: Store antibody at -20°C for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: RPS6KB1
- ADDITIONAL NAMES: S6K, PS6K, S6K1, STK14A, p70-S6K, p70S6KA, p70-alpha, S6K-beta-1, p70(S6K)-alpha, MAPTL, MTBT1, TAU, KS6B1, P70-S6K, RPS6KB1, S6K
- Protein Accession Number: NP_003152.1
- PROTEIN GI NUMBER: 4506737
- NCBI GENE ID NUMBER: 6198
Background
- Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.
- 1: Xiao-Feng, et al. (2003) Le1 30 Volume 22: 484-497An WL, et al. (2003) Am J Pathol. 163 (2): 591-607. Le XF, et al. (2003) Oncogene. 22 (4): 484-97
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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