Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Rat
- IMMUNOGEN: This P2RY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the Central region of human P2RY1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 42 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: P2RY1
- ADDITIONAL NAMES: P2Y purinoceptor 1, P2Y1, ATP receptor, Purinergic receptor, P2RY1
- Protein Accession Number: P47900
- PROTEIN GI NUMBER: 1352692
- NCBI GENE ID NUMBER: 5028
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- The product of this gene belongs to the family ofG-protein coupled receptors. This family has several receptorsubtypes with different pharmacological selectivity, which overlapsin some cases, for various adenosine and uridine nucleotides. Thisreceptor functions as a receptor for extracellular ATP and ADP. Inplatelets binding to ADP leads to mobilization of intracellularcalcium ions via activation of phospholipase C, a change inplatelet shape, and probably to platelet aggregation. [provided byRefSeq].
- 1: Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- 2: Maloney, S.F., et al. Integr Biol (Camb) 2(4):183-192(2010)
- 3: Nisar, S., et al. Traffic 11(4):508-519(2010)
- 4: Kumar, T.S., et al. J. Med. Chem. 53(6):2562-2576(2010)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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