OXT Antibody
CATALOG NUMBER: 15-970- Clonality: Polyclonal
- Tested Applications: IHC, WB
- Host Species: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Conjugate: Unconjugated
- Size: 50 uL
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human, Mouse, Rat
- IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human OXT (NP_000906.1).
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: IHC, WB
- APPLICATION NOTE: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200 - POSITIVE CONTROL 1: A549
- POSITIVE CONTROL 2: NCI-H460
- POSITIVE CONTROL 3: LO2
- POSITIVE CONTROL 4: HepG2
- POSITIVE CONTROL 5: Mouse liver
- POSITIVE CONTROL 6: Rat liver
- PREDICTED MOLECULAR WEIGHT: Observed: 13kDa
Properties
- PURIFICATION: Affinity purification
- CLONALITY: Polyclonal
- ISOTYPE: IgG
- PHYSICAL STATE: Liquid
- BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at -20°C. Avoid freeze / thaw cycles.
Additional Info
- NCBI OFFICIAL SYMBOL: OXT
- ADDITIONAL NAMES: oxytocin-neurophysin I, preproprotein, oxytocin-neurophysin I, OT-NPI, OT, MGC126892, MGC126890, oxytocin, prepro- (neurophysin I), OXT
- NCBI GENE ID NUMBER: 5020
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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