OSTM1 Antibody
CATALOG NUMBER: 59-814- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 400 ul
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- HOMOLOGY: Predicted species reactivity based on immunogen sequence: Mouse
- IMMUNOGEN: This OSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human OSTM1.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 37 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: OSTM1
- ADDITIONAL NAMES: Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit, OSTM1, GL
- Protein Accession Number: Q86WC4
- PROTEIN GI NUMBER: 51316434
- NCBI GENE ID NUMBER: 28962
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene encodes a protein that may be involved in thedegradation of G proteins via the ubiquitin-dependent proteasomepathway. The encoded protein binds to members of subfamily A of theregulator of the G-protein signaling (RGS) family through anN-terminal leucine-rich region. This protein also has a centralRING finger-like domain and E3 ubiquitin ligase activity. Thisprotein is highly conserved from flies to humans. Defects in thisgene may cause the autosomal recessive, infantile malignant form ofosteopetrosis.
- 1: Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
- 2: Mazzolari, E., et al. Am. J. Hematol. 84(8):473-479(2009)
- 3: Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)
- 4: Feigin, M.E., et al. Cell. Signal. 20(5):949-957(2008)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
$65 Standard Overnight flat rate for as many products shipped within the United States.
$35 Dry Ice Shipment fee may be required on some items.
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