OCT-4 Antibody
CATALOG NUMBER: 79-645- Clonality: Polyclonal
- Tested Applications: WB
- Host Species: Rabbit
- Species Reactivity: Human
- Conjugate: Unconjugated
- Size: 0.1 mg
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- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: OCT-4 antibody was raised against a peptide sequence around aa.232~236 (R-K-R-T-S) derived from OCT-4.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: Western Blot: 1:1000
- SPECIFICITY: This antibody detects endogenous level of total OCT-4 protein.
- PREDICTED MOLECULAR WEIGHT: 45 kDa
Properties
- PURIFICATION: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- CLONALITY: Polyclonal
- PHYSICAL STATE: Liquid
- BUFFER: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- CONCENTRATION: 1 mg/mL
- STORAGE CONDITIONS: Store antibody at -20°C for up to one year.
Additional Info
- NCBI OFFICIAL SYMBOL: POU5F1
- ADDITIONAL NAMES: OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4, CDKN6, Otc3
- Protein Accession Number: NP_002692.2
- PROTEIN GI NUMBER: 42560248
- NCBI GENE ID NUMBER: 5460
Background
- Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency
- 1: Pesce, M. and Scholer, H. R. (2001) Stem Cells 19, 271-278. Pan, G. and Thomson, J. A. (2007) Cell Res 17, 42-9. Cauffman, G. et al. (2006) Stem Cells 24, 2685-91.
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Shipping Info
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$35 Dry Ice Shipment fee may be required on some items.
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