Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This NXF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the N-terminal region of human NXF5.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
- PREDICTED MOLECULAR WEIGHT: 46 kDa
Properties
- PURIFICATION: This antibody is purified through a protein A column, followed by peptide affinity purification.
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: NXF5
- ADDITIONAL NAMES: Nuclear RNA export factor 5, TAP-like protein 1, TAPL-1, NXF5, TAPL1
- Protein Accession Number: Q9H1B4
- PROTEIN GI NUMBER: 20978537
- NCBI GENE ID NUMBER: 55998
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- This gene is one member of a family of nuclear RNA exportfactor genes. The encoded protein can bind RNA, and is implicatedin mRNA nuclear export. However, this protein has lost severalC-terminal protein domains found in other family members that arerequired for export activity, and may be an evolving pseudogene.Alternatively spliced transcript variants have been described, butmost are candidates for nonsense-mediated decay (NMD) and may notexpress proteins in vivo.
- 1: Tarpey, P.S., et al. Nat. Genet. 41(5):535-543(2009)
- 2: Hillman, R.T., et al. Genome Biol.(2), R8 (2004) :
- 3: Frints, S.G., et al. Am. J. Med. Genet.119A (3), 367-374 (2003) :
- 4: Jun, L., et al. Curr. Biol. 11(18):1381-1391(2001)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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