Specifications
- HOST SPECIES: Rabbit
- SPECIES REACTIVITY: Human
- IMMUNOGEN: This NUP62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-520 amino acids from the C-terminal region of human NUP62.
- CONJUGATE: Unconjugated
- TESTED APPLICATIONS: Flow, IHC-P, WB
- APPLICATION NOTE: For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50 - PREDICTED MOLECULAR WEIGHT: 53 kDa
Properties
- PURIFICATION: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
- CLONALITY: Polyclonal
- ISOTYPE: Rabbit Ig
- PHYSICAL STATE: Liquid
- BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
- CONCENTRATION: batch dependent
- STORAGE CONDITIONS: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
- NCBI OFFICIAL SYMBOL: NUP62
- ADDITIONAL NAMES: Nuclear pore glycoprotein p62, 62 kDa nucleoporin, Nucleoporin Nup62, NUP62
- Protein Accession Number: P37198
- PROTEIN GI NUMBER: 134047855
- NCBI GENE ID NUMBER: 23636
- USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background
- NUP62 is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This protein is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. The protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals.
- 1: Stochaj,U., Banski,P. Exp. Cell Res. 312 (13), 2490-2499 (2006)
- 2: Basel-Vanagaite,L., Muncher,L. Ann. Neurol. 60 (2), 214-222 (2006)
- 3: Guan,T., Muller,S. Mol. Biol. Cell(11), 1591-1603 (1995)
Disclaimer
- FOR RESEARCH USE ONLY
For additional information, visit ProSci's Terms & Conditions Page. - Disclaimer: Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
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